Due to the public health risk associated with histamine contamination, further requirements related to the quality of raw materials have been added to the Raw materials section of the monograph on Products of fermentation (1468).

The implementation date for the revised monograph was 1 April 2018. The pdf version of the text is available here. The revised monograph has already been added to the online version of the Ph. Eur., starting with Supplement 9.4. It will be included in the printed and downloadable versions starting with Supplement 9.6.