The newly released 10th Edition of the European Pharmacopoeia, contains 2 420 monographs and 373 general texts (including general monographs and methods of analysis), as well as around 2 780 descriptions of reagents. In total, 114 new monographs have been introduced, of these 17 concern active substances of high medical interest covering key therapeutic classes, such as antineoplastics, immunosuppressants, anti-arrhythmics, anti-thrombotics, antiretrovirals or analgesics; and 7 monographs concern finished products containing chemically defined active substances.